Substance
ID:717488
Names and Identifiers
IUPAC name
ethyl prop-2-ynoate
IUPAC Traditional name
ethyl propiolate
Synonyms
Ethyl acetylenecarboxylateEthyl propiolate丙炔酸乙酯Propiolic acid ethyl ester
Registration numbers
CAS Number
EC Number
Beilstein Number
MDL Number
Properties
Safety Information
GHS Pictograms
Flammable gases, category 1
Flammable aerosols, categories 1,2
Flammable liquids, categories 1,2,3
Self-reactive substances and mixtures, Types B,C,D,E,F
Pyrophoric liquids, category 1
Pyrophoric solids, category 1
Self-heating substances and mixtures
Substances and mixtures, which in contact with water, emit flammable gases, categories 1,2,3
Organic peroxides, Types B,C,D,E,F
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Risk Statements
10-36/37/38
Safety Statements
26-37-60
Hazard Class
3
GHS Hazard statements
H226-H315-H319-H335
European Hazard Symbols
Irritant (Xi)Packing Group
III
UN Number
UN3272
GHS Precautionary statements
P210-P241-P303+P361+P353-P305+P351+P338-P405-P501A
TSCA Listed
否
Physical Property
Refractive Index
1.4120
Boiling Point
118-120°C
Flash Point
23°C(73°F)
Melting Point
9°C
Density
0.963
Product Information
Purity
99%
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Regio- and stereospecific hydrohalogenation of propiolic acid derivatives is illustrated by the conversion of ethyl propiolate to (Z)-3-bromo-2-propenoate in the presence of LiBr + acetic acid in acetonitrile: J. Org. Chem., 57, 709 (1992); Org. Synth. Coll., 9, 412 (1998).
• n-BuLi gives the alkynyllithium derivative, stable at low temperatures: J. Org. Chem., 45, 28 (1980). For use in a sequence for the synthesis of butenolides, see: J. Am. Chem. Soc., 101, 1544 (1979):
• Conjugate addition of allylic alcohols in the presence of trimethylamine proceeds via an intermediate betaine and leads to allyl vinyl ethers which undergo the Claisen rearrangement to give δ-unsaturated aldehydes: J. Org. Chem., 48, 5406 (1983); Org. Synth. Coll., 8, 536 (1993):
