Substance

ID:717105

Names and Identifiers
IUPAC name
pyridin-2-ol
IUPAC Traditional name
2-pyridone
Synonyms
2-Hydroxypyridine2-羟基吡啶2(1H)-Pyridone2-Pyridinol
Registration numbers
CAS Number
EC Number
MDL Number
Beilstein Number
Properties
Safety Information
European Hazard Symbols
Toxic Toxic (T)
TSCA Listed
RTECS
UV1144050
Packing Group
III
GHS Pictograms
GHS06
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
UN Number
UN2811
Safety Statements
26-36/37-45
Risk Statements
25-36/37/38
GHS Precautionary statements
P261-P301+P310-P305+P351+P338-P302+P352-P405-P501A
Hazard Class
6.1
GHS Hazard statements
H301-H315-H319-H335
Physical Property
Flash Point
210°C(410°F)
Density
1.39
Melting Point
102-111°C
Boiling Point
280-281°C
Product Information
Purity
98+%
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• For use of 2-pyridyl esters as active esters in peptide coupling, see: J. Chem. Soc.(C), 2896 (1971); Chem. Ber., 118, 468 (1985). The group can be introduced on to the N-protected peptide using DCC in pyridine, and is displaced by the amino-residue under mild conditions. For peptide reagents, see Appendix 6. Similar methodology has also been used in an improved preparation of trichloroethyl esters: Synthesis, 24 (1979).
• Bifunctional catalyst for a wide variety of acylation reactions. See, for example: J. Chem. Soc. (C), 89 (1969).
• Reacts with SOCl2 to form di-2-pyridyl sulfite, a useful reagent for in situ formation of N-sulfinylamines, nitriles, isocyanides and carbodiimides under mild conditions: Tetrahedron Lett., 27, 1925 (1986).