Substance
ID:716952
Names and Identifiers
IUPAC name
(chloromethyl)trimethylsilane
IUPAC Traditional name
(chloromethyl)trimethylsilane
Synonyms
(氯甲基)三甲基硅烷(Chloromethyl)trimethylsilane
Registration numbers
CAS Number
Beilstein Number
EC Number
MDL Number
Properties
Physical Property
Refractive Index
1.4180
Density
0.886
Boiling Point
97-98°C
Flash Point
-2°C(28°F)
Safety Information
European Hazard Symbols
Irritant (Xi)
Flammable (F)TSCA Listed
是
GHS Hazard statements
H224-H315-H319-H335
Safety Statements
9-16-23-26-33-37
Risk Statements
11-36/37/38
GHS Precautionary statements
P210-P241-P303+P361+P353-P305+P351+P338-P405-P501A
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Flammable gases, category 1
Flammable aerosols, categories 1,2
Flammable liquids, categories 1,2,3
Self-reactive substances and mixtures, Types B,C,D,E,F
Pyrophoric liquids, category 1
Pyrophoric solids, category 1
Self-heating substances and mixtures
Substances and mixtures, which in contact with water, emit flammable gases, categories 1,2,3
Organic peroxides, Types B,C,D,E,F
Storage Warning
Moisture Sensitive
UN Number
UN1993
Hazard Class
3
Packing Group
II
Product Information
Purity
98%
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Metallation gives useful precursors of various organosilicon compounds. For use of the Grignard in the olefination of ketones, see: J. Org. Chem., 39, 3264 (1974); 52, 281 (1987). For Ni-catalyzed reaction of the Grignard with allylic dithioacetals, see: J. Org. Chem., 53, 5582 (1988); Org. Synth. Coll., 9, 727 (1998); for an example with reaction scheme, see trans-Cinnamaldehyde, A14689.
• Treatment with s-BuLi at -78o gives ɑ-lithio-ɑ-chloromethyltrimethylsilane which reacts with aldehydes and ketones to give ɑ?-epoxy silanes, readily hydrolyzed to homologated aldehydes: Tetrahedron, 39, 867 (1983):
• For a review of the chemistry of chloromethyltrimethylsilane, see: Synthesis, 717 (1985).