Substance
ID:716926
Names and Identifiers
IUPAC Traditional name
dimethyl methylphosphonate
IUPAC name
dimethyl methylphosphonate
Synonyms
Dimethyl methylphosphonateDMMPMethylphosphonic acid dimethyl ester甲基磷酸二甲酯
Registration numbers
CAS Number
EC Number
MDL Number
Beilstein Number
Merck Index
Properties
Safety Information
GHS Precautionary statements
P210-P280-P281-P305+P351+P338-P405-P501A
Safety Statements
53-45-61
TSCA Listed
是
European Hazard Symbols
Toxic (T)GHS Hazard statements
H340-H319-H227-H402-H412
Risk Statements
46-36-52/53
GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
RTECS
SZ9120000
Physical Property
Density
1.16
Flash Point
68°C(154°F)
Boiling Point
180-181°C
Refractive Index
1.4130
Product Information
Purity
97%
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• The lithio-derivative reacts with esters to give ?-ketophosphonates, useful precursors of ɑ?-unsaturated ketones by Horner-Wadsworth-Emmons olefination: J. Am. Chem. Soc., 88, 5654 (1966). An intramolecular version leads to cyclopentenones: Synth. Commun., 5, 1 (1975); Tetrahedron Lett., 22, 257 (1981). Dimethyl glutarate gives the 3-(phosphonatomethyl)cyclohexenone, olefination of which affords the corresponding 3-alkenylcycloalkenone. Dimethyl succinate also gives this reaction, but in lower yield; higher diesters give acyclic products: J. Org. Chem., 59, 1943 (1994):
• See also Diethyl methylphosphonate, A14772 and Appendix 1.