Substance
ID:716238
Names and Identifiers
IUPAC Traditional name
tetramethylammonium chloride
IUPAC name
tetramethylazanium chloride
Synonyms
Tetramethylammonium chloride四甲基氯化铵
Registration numbers
CAS Number
MDL Number
EC Number
Beilstein Number
Properties
Safety Information
Storage Warning
Hygroscopic
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
GHS Precautionary statements
P280H-P305+P351+P338-P309-P310
Safety Statements
26-36/37-45
Hazard Class
6.1
Packing Group
II
RTECS
BS7700000
TSCA Listed
是
Risk Statements
21-25-36/37/38
UN Number
UN2811
GHS Hazard statements
H301-H311-H315-H319-H335
European Hazard Symbols
Toxic (T)Physical Property
Melting Point
>300°C
Density
1.17
Product Information
Purity
97%, may cont. ca 3% silica as anticaking agent
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Thermally-stable phase-transfer catalyst (see Appendix 2) which has been used in nucleophilic displacement reactions of aryl nitro groups with KF in tetramethylene sulfone: J. Org. Chem., 56, 6406 (1991). A detailed study of the halex Cl - /F - exchange reaction of activated aryl chlorides, for example the conversion of 1,2-dichloro-4-nitrobenzene to 2-chloro-1-fluoro-4-nitrobenzene in DMSO at 120oC showed tetramethylammonium chloride to be superior to other common phase-transfer catalysts. It was necessary to pre-dry the catalyst to <0.2% water to avoid competition from hydrolytic displacement: Chem. Commun., 297 (1996).
• Compare also Tetraphenylphosphonium bromide, A15860 and Tetraphenylphosphonium chloride, A10575.