Substance
ID:715496
Names and Identifiers
IUPAC Traditional name
methylpyrrolidone
IUPAC name
1-methylpyrrolidin-2-one
Synonyms
N-Methyl-2-Pyrrolidone1-甲基-2-吡咯烷酮1-Methyl-2-pyrrolidinoneN-Methylbutyrolactam
Registration numbers
Beilstein Number
Merck Index
CAS Number
EC Number
MDL Number
Properties
Physical Property
Melting Point
-24°C
Flash Point
86°C(187°F)
Boiling Point
204°C
Density
1.033
Refractive Index
1.4705
Product Information
Purity
99+%
Safety Information
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
GHS Hazard statements
H360-H315-H319-H335-H227
GHS Precautionary statements
P210-P305+P351+P338-P302+P352-P321-P405-P501A
Risk Statements
61-36/37/38
RTECS
UY5790000
European Hazard Symbols
Toxic (T)TSCA Listed
是
Safety Statements
53-45
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Nucleophilic displacement reactions with CN-: J. Chem. Soc., 954 (1962). Preparation of thiophenols from unactivated aryl chlorides and Na alkanethiolates: J. Org. Chem., 56, 3728 (1991). Reaction of thiophenol and potassium carbonate in uncatalyzed substitution reactions of chloroanilines and chloroanilides: J. Org. Chem., 56, 862 (1991). Synthesis of alkylaryl and alkylheteroaryl ethers, catalyzed by Cu(I): Tetrahedron, 48, 3633 (1992).
• Water-miscible, high-boiling dipolar aprotic solvent, compare N,N-Dimethylformamide, A13547 and Dimethyl sulfoxide, A13280, used in a wide variety of reactions, e.g.: