Substance
ID:715152
Names and Identifiers
IUPAC Traditional name
pyridium chlorochromiumoylolate
IUPAC name
pyridin-1-ium chlorochromiumoylolate
Synonyms
PCC氯铬酸吡啶鎓Pyridinium chlorochromate
Properties
Product Information
Purity
98%
Physical Property
Melting Point
ca 206°C dec.
Safety Information
GHS Pictograms
Hazardous to the aquatic environment
Acute hazard, category1
Chronic hazard, categories 1,2
Oxidizing gases, category 1
Oxidizing liquids, categories 1,2,3
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
European Hazard Symbols
Oxidising (O)
Toxic (T)
Nature polluting (N)UN Number
UN1479
Storage Warning
Moisture Sensitive
Packing Group
II
GHS Hazard statements
H350-H272-H400-H410-H317
Risk Statements
49-8-43-50/53
TSCA Listed
是
GHS Precautionary statements
P221-P210-P302+P352-P321-P405-P501A
Safety Statements
53-45-60-61
Hazard Class
5.1
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Mild, selective oxidant for alcohols to aldehydes or ketones: Tetrahedron Lett., 2647 (1975); review: Synthesis, 245 (1982). Superior results have been reported with a catalytic amount of acetic acid: Tetrahedron, 46, 4417 (1990). Adsorption of the reagent onto alumina simplifies work-up and enhances reactivity in hydrocarbon solvents: Synthesis, 223 (1980). Improved results have also been obtained in the presence of silica gel, where reaction times are shortened by sonication: J. Org. Chem., 54, 5387 (1989). Oxidation of methylarenes to benzaldehydes has been reported. Selective mono-oxidation of xylenes to tolualdehydes can be achieved: Synlett, 2769 (2005).
• Trialkyl boranes are also oxidized to carbonyl compounds, non-terminal boranes giving ketones: J. Organomet. Chem., 162, C9 (1978) and terminal boranes giving aldehydes: J. Organomet. Chem., 172, C20 (1979). Similarly, aldehydes can be prepared from terminal alkenes by oxidation of their adducts with thexylborane: Synthesis, 151 (1980).
• For 18-crown-6 complexes of chlorochromates as mild, selective oxidants, see: J. Org. Chem., 60, 2267 (1995). See also 1H-Pyrazole, A14186.
• For a brief feature on novel oxidation reactions with this reagent, see: Synlett, 741 (2003).
• In THF, arylhydroxylamines are selectively oxidized to nitroso compounds: Synth. Commun., 22, 1683 (1992).