Substance

ID:715044

Phenyl isothiocyanate

Names and Identifiers
IUPAC Traditional name
phenylisothiocyanate
IUPAC name
isothiocyanatobenzene
Synonyms
Phenyl isothiocyanate异硫氰酸苯酯
Registration numbers
MDL Number
CAS Number
Beilstein Number
EC Number
Merck Index
Properties
Safety Information
European Hazard Symbols
Toxic Toxic (T)
Nature polluting Nature polluting (N)
GHS Pictograms
GHS09
Hazardous to the aquatic environment
Acute hazard, category1
Chronic hazard, categories 1,2
GHS06
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
GHS08
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
GHS05
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
Risk Statements
23/24/25-34-42/43-50/53
Storage Warning
Moisture Sensitive
GHS Precautionary statements
P210-P301+P310-P303+P361+P353-P304+P340-P305+P351+P338-P320-P330-P361-P405-P501A
RTECS
NX9275000
Safety Statements
23-26-36/37/39-45-60-61
Packing Group
II
GHS Hazard statements
H300-H310-H330-H317-H334-H314-H318-H400-H410-H227
UN Number
UN2927
TSCA Listed
Hazard Class
6.1
Physical Property
Melting Point
-21°C
Boiling Point
220-221°C
Density
1.131
Flash Point
87°C(188°F)
Refractive Index
1.6500
Product Information
Purity
97%
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• For general reactions of isothiocyanates, see Appendix 3.
• Derivatizing agent for amino groups. Introduced by Edman for the determination of amino acid sequence by conversion to the thiourea, acid cleavage of the peptide bond and alkaline hydrolysis of the derived thiohydantoin: Acta Chem. Scand., 4, 277 (1950); Arkiv. Kemi., 14, 291 (1959). The thiourea can also be cleaved with TFA: Nature, 227, 716 (1970), or by peracid oxidation: Chem. Ber., 89, 2288 (1956).