Substance
ID:714353
Names and Identifiers
IUPAC name
methyl 2-bromoacetate
IUPAC Traditional name
methyl 2-bromoacetate
Synonyms
Methyl bromoacetate溴乙酸甲酯Bromoacetic acid methyl ester
Properties
Safety Information
RTECS
AF6300000
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
GHS Precautionary statements
P210-P301+P310-P303+P361+P353-P305+P351+P338-P361-P405-P501A
Hazard Class
6.1
Risk Statements
25-34
GHS Hazard statements
H301-H311-H331-H314-H318-H227
European Hazard Symbols
Toxic (T)Safety Statements
20-23-26-36/37/39-45-60
TSCA Listed
是
UN Number
UN2643
Packing Group
II
Physical Property
Flash Point
62°C(143°F)
Refractive Index
1.4585
Melting Point
-50°C
Density
1.655
Boiling Point
144-145°C
Product Information
Purity
98+%
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Addition of the organozinc derivative to nitriles (Blaise reaction), gives ?-amino acrylates, which can be hydrolyzed to ?-keto esters. For conditions allowing the use of hindered nitriles, see: J. Org. Chem., 48, 3833 (1983):
• The reaction with aldehydes in the presence of zinc and tri-n-butylphosphine gives ɑ?-unsaturated esters directly: Tetrahedron Lett., 29, 6119 (1988).
• For further reactions of ɑ-bromo esters, see Ethyl bromoacetate, A10448.