Substance
ID:714098
Names and Identifiers
IUPAC Traditional name
phthalan
IUPAC name
1,3-dihydro-2-benzofuran
Synonyms
1,3-Dihydrobenzo[c]furan1,3-二氢异苯并呋喃1,3-DihydroisobenzofuranPhthalan
Registration numbers
MDL Number
CAS Number
EC Number
Beilstein Number
Properties
Physical Property
Refractive Index
1.5460
Flash Point
63°C(145°F)
Density
1.094
Boiling Point
192°C
Product Information
Purity
98%
Safety Information
GHS Precautionary statements
P210-P280-P370+P378A-P403+P235-P501A
TSCA Listed
否
GHS Hazard statements
H227
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Treatment of phthalan with excess Li metal in the presence of 4,4'-Di-tert-butylbiphenyl, B21470, results in opening of the furan ring. Sequential introduction of two different electrophiles can be effected in the resulting bis-benzylic species, consequently phthalan can be regarded as an o-xylene dianion synthon. This approach provides a convenient access to diols and hydroxy acids which can be readily dehydrated to benzo-fused 6- or 7-membered cyclic ethers or lactones: Tetrahedron, 51, 3351 (1995); see also: J. Org. Chem., 61, 4913 (1996); Tetrahedron Lett., 39, 7759 (1998).
• For use in synthesis of nine-membered cyclic dione ethers, see: Synlett, 909 (1993).