Substance
ID:713392
Names and Identifiers
IUPAC Traditional name
1,3-dichloroacetone
IUPAC name
1,3-dichloropropan-2-one
Synonyms
1,3-Dichloroacetone1,3-二氯丙酮1,3-Dichloro-2-propanone
Registration numbers
CAS Number
MDL Number
Beilstein Number
EC Number
Merck Index
Properties
Physical Property
Boiling Point
172-173°C
Melting Point
40-44°C
Density
1.383
Flash Point
95°C(203°F)
Refractive Index
1.4400
Safety Information
European Hazard Symbols
Nature polluting (N)
Highly toxic (T+)UN Number
UN2649
GHS Pictograms
Hazardous to the aquatic environment
Acute hazard, category1
Chronic hazard, categories 1,2
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
GHS Precautionary statements
P280-P305+P351+P338-P302+P352-P309-P310-P501A
Risk Statements
24-26/28-34-68-50/53
Hazard Class
6.1
RTECS
UC1430000
Safety Statements
26-28-36/37/39-45-60-61
TSCA Listed
是
GHS Hazard statements
H300-H310-H330-H314-H318-H341-H400-H410
Packing Group
II
Product Information
Purity
96%
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Successive reaction with a Grignard reagent and Li metal leads to 1-substituted cyclopropanols, which rearrange on thermolysis to ethyl ketones: Synthesis, 647 (1983):
• The cyclization can also be induced by ethyl radicals, generated from ethylmagnesium bromide and FeCl3. This method is applicable only to 1-arylcyclopropanols: J. Org. Chem., 29, 2813 (1964); 43, 3602 (1978); Org. Synth. Coll., 5, 1058 (1973).
• Formation of the acetal followed by treatment with NaNH2 provides a route to cyclopropenones: Tetrahedron, 48, 2045 (1992).