Substance
ID:682
Names and Identifiers
Synonyms
HalazepamHalazepamum [INN-Latin]
IUPAC Traditional name
halazepam
IUPAC name
7-chloro-5-phenyl-1-(2,2,2-trifluoroethyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one
Brand Name
PaxipamPacinone
Properties
Physical Property
Hydrophobicity(logP)
4.3
Molecule Details
Drug Groups
illicit; approved
Description
Halazepam is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It is a trifluoromethyl derivative of nordazepam. While its structure may be similar to chlordiazepoxide and diazepam, it has both less toxicity and less tendency to cause paradoxical hostility and aggression than either of them. [Wikipedia]
Indication
Used to relieve anxiety, nervousness, and tension associated with anxiety disorders.
Affected Organisms
Humans and other mammals
Biotransformation
Hepatic.
References
•
Fann WE, Pitts WM, Wheless JC: Pharmacology, efficacy, and adverse effects of halazepam, a new benzodiazepine. Pharmacotherapy. 1982 Mar-Apr;2(2):72-9.
[Pubmed]
External Links
Molecular Spectra
No Data Available
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References
• Fann WE, Pitts WM, Wheless JC: Pharmacology, efficacy, and adverse effects of halazepam, a new benzodiazepine. Pharmacotherapy. 1982 Mar-Apr;2(2):72-9. Pubmed