Substance
ID:553
Names and Identifiers
Brand Name
PirenzepinTabeBisvanilUlcosanGasterilLeblonPirenzepine GastrozepinGastrozepinPirenzepina [INN-Spanish]Pirenzepinum [INN-Latin]
IUPAC name
2-[2-(4-methylpiperazin-1-yl)acetyl]-2,4,9-triazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-10-one
Synonyms
Pirenzepine
IUPAC Traditional name
pirenzepine
Properties
Physical Property
Hydrophobicity(logP)
0.6
Molecule Details
Drug Groups
approved
Description
An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as cimetidine and ranitidine. It is generally well tolerated by patients. [PubChem]
Indication
For the treatment of peptic ulcer, gastric ulcer, and duodenal ulcer.
Pharmacology
Pirenzepine belongs to a group of medications called antispasmodics/anticholinergics. These medications are used to relieve cramps or spasms of the stomach, intestines, and bladder. Pirenzepine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer. It may also be used to prevent nausea, vomiting, and motion sickness.
Affected Organisms
Humans and other mammals
References
•
Czepita D: [Fundamentals of modern treatment of myopia] Ann Acad Med Stetin. 2005;51(2):5-9.
[Pubmed]
External Links
Molecular Spectra
No Data Available
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References
• Czepita D: [Fundamentals of modern treatment of myopia] Ann Acad Med Stetin. 2005;51(2):5-9. Pubmed