Substance

ID:512

Names and Identifiers
Brand Name
Guanabenz AcetateGBZGuanabenz(USAN)Guanabenzo [INN-Spanish]Guanabenzum [INN-Latin]Guanabenz [USAN:INN]WytensinWy 8678 base
IUPAC name
2-{[(2,6-dichlorophenyl)methylidene]amino}guanidine
IUPAC Traditional name
guanabenz
Synonyms
Guanabenz
Registration numbers
PubChem CID
5702063
PubChem SID
46505200
CAS Number
5051-62-7
Properties
Physical Property
Hydrophobicity(logP)
3.2
Molecule Details
Drug Groups
approved
Description
An alpha-2 selective adrenergic agonist used as an antihypertensive agent. [PubChem]
Indication
For management of High blood pressure
Pharmacology
Guanabenz, a centrally acting α-2 adrenergic agonist, is indicated for treatment of hypertension.
Toxicity
Excessive contraction of the pupils, irritability, low blood pressure, sleepiness, slow heartbeat, sluggishness
Affected Organisms
Humans and other mammals
Biotransformation
Hepatic
Absorption
Approximately 75% absorbed from gastrointestinal tract
Half Life
6 hours.
Protein Binding
90%
External Links
• [Wikipedia]
• [PDRhealth]
• [Drugs.com]
Molecular Spectra
No Data Available
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References
No Data Available
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