Substance
ID:4593
Names and Identifiers
Synonyms
SparteineSparteinumGenisteineSparteinum sulfuricumlupinidine(-)-sparteinePachycarpined-SparteineEsparteina
IUPAC Traditional name
(1S,2S,9S,10S)-7,15-diazatetracyclo[7.7.1.0^{2,7}.0^{10,15}]heptadecane
IUPAC name
(1S,2S,9S,10S)-7,15-diazatetracyclo[7.7.1.0^{2,7}.0^{10,15}]heptadecane
Properties
Physical Property
Solubility
3.04 mg/mL at 22 oC [YALKOWSKY,SH & DANNENFELSER,RM (1992)]
Molecule Details
Drug Groups
experimental
Description
Sparteine is a class 1a antiarrhythmic agent; a sodium channel blocker. It is an alkaloid and can be extracted from scotch broom. It is the predominant alkaloid in Lupinus mutabilis, and is thought to chelate the bivalents calcium and magnesium. It is not FDA approved for human use as an antiarrhythmic agent, and it is not included in the Vaughn Williams classification of antiarrhythmic drugs.
Affected Organisms
Humans and other mammals
External Links
Molecular Spectra
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References
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