Substance
ID:4545
Names and Identifiers
Synonyms
Ecabetum [inn-latin]12-sulfodehydroabietic acidEcabet [inn]ecabet sodiumEcabet (inn)Ecabet13-Isopropyl-12-sulfopodocarpa-8,11,13-trien-15-oic acidEcabetum
IUPAC Traditional name
ecabet
Brand Name
Gastrom
IUPAC name
(1R,4aS,10aR)-1,4a-dimethyl-7-(propan-2-yl)-6-sulfo-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid
Properties
No Data Available
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Molecule Details
Drug Groups
approved; investigational
Description
Ecabet is a prescription eye drop for the treatment of dry eye syndrome. Ecabet represents a new class of molecules that increases the quantity and quality of mucin produced by conjunctival goblet cells and corneal epithelia. Mucin is a glycoprotein component of tear film that lubricates while retarding moisture loss from tear evaporation. Ecabet is currently marketed in Japan as an oral agent for treatment of gastric ulcers and gastritis.
Indication
For the treatment of reflux oesophagitis and peptic ulcer disease.
External Links
Molecular Spectra
No Data Available
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References
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