Substance

ID:4521

Names and Identifiers
Synonyms
FluspirileneFluspirileno [inn-spanish]Fluspirilenum [inn-latin]
IUPAC Traditional name
imap
Brand Name
ImapRedeptinLopac-F-100
IUPAC name
8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Registration numbers
CAS Number
PubChem SID
PubChem CID
Properties
Physical Property
Hydrophobicity(logP)
5.86 [HANSCH,C ET AL. (1995)]
Solubility
0.01 mg/mL at 25 oC [MERCK INDEX (1996)]
Molecule Details
Drug Groups
approved
Description
A long-acting injectable antipsychotic agent used for chronic schizophrenia.
Indication
Used for the treatment of schizophrenia.
Pharmacology
Fluspirilene is a relatively long-acting injectable depot antipsychotic drug used for schizophrenia. Fluspirilene does not differ greatly from other depot antipsychotics (fluphenazine decanoate, fluphenazine enathate, perphenazine onanthat, pipotiazine undecylenate) with respect to treatment efficacy, response or tolerability. Outcomes suggest that fluspirilene does not differ significantly from oral antipsychotics or in different weekly regimens, although much cannot be inferred because of the shortage of trials.
Affected Organisms
Humans and other mammals
External Links
Molecular Spectra
No Data Available
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References
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