Substance
ID:4517
Names and Identifiers
Brand Name
CapilanCyclobralSepyronSpasmioneSpasmocyclonCyclergineCyclomandolDilatanArto-espasmolClandilonVasodylCiclospasmolCyclospasmolSaiclateSancyclanCyclolytNatilNovodilPerebralSpasmocyclone
IUPAC name
3,3,5-trimethylcyclohexyl 2-hydroxy-2-phenylacetate
Synonyms
3,5,5-Trimethylcyclohexyl amygdalateCyclandelic acidCiclandelato [inn-spanish]3,5,5-Trimethylcyclohexyl mandelateCyclandelate3,3,5-Trimethylcyclohexyl mandelateCyclandelatum [inn-latin]
IUPAC Traditional name
cyclandelate
Properties
No Data Available
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Molecule Details
Drug Groups
approved
Description
A direct-acting smooth muscle relaxant used to dilate blood vessels. It may cause gastrointestinal distress and tachycardia. Cyclandelate is not approved for use in the U.S. or Canada, but is approved in various European countries.
Indication
Used in the treatment of various blood vessel diseases (e.g., claudication, arteriosclerosis and Raynaud's disease) and nighttime leg cramps.
Pharmacology
Cyclandelate is in a class of drugs called vasodilators. Cyclandelate relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily.
Toxicity
Acute oral toxicity (LD50): 3950 mg/kg [Guinea pig]
Affected Organisms
Humans and other mammals
Absorption
Well absorbed following oral administration.
External Links
Molecular Spectra
No Data Available
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References
No Data Available
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