Substance
ID:449864
Names and Identifiers
IUPAC name
({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid
Synonyms
VireadApropovir9-[2-(Phosphonomethoxy)propyl]adenineTenofovir
IUPAC Traditional name
({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Antiretroviral drugs
Anti-HIV agent
Pharmacology Properties
Mechanism of Action
Reverse transcriptase inhibitor
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Hatse, S. et al., Int. J. Cancer, 1998, 76, 595-600
• van Rompay, K.K.A. et al., Antimicrob. Agents Chemother., 1996, 40, 2586-2591
• Mulato, A.S. et al., Antiviral Res., 1997, 36, 91-97
• Eur. Pat., 1986, Ceskoslovenska, 206 459; CA, 106, 214308n
• Balzarini, J. et al., Biochem. Biophys. Res. Commun., 1996, 219, 337-341
• Naesens, L. et al., Antimicrob. Agents Chemother., 1998, 42, 1568-1573
• Arimilli, M.N. et al., Antiviral Chem. Chemother., 1997, 8, 557-564
• Robbins, B.L. et al., Antimicrob. Agents Chemother., 1998, 42, 612-617; 1484-1487