Substance
ID:449863
Names and Identifiers
IUPAC name
(3R)-3-amino-1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
Synonyms
MK-0431Sitagliptin
IUPAC Traditional name
(3R)-3-amino-1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
Registration numbers
CAS Number
Properties
Pharmacology Properties
Mechanism of Action
Dipeptidyl peptidase-4 (DPP-4) inhibitor
Product Information
Application(s)
Antidiabetic drug
Molecule Details
No Data Available
Click here to submit data
Molecular Spectra
No Data Available
Click here to submit data
References
• Herman GA; Stevens C, Van Dyck K, Bergman A, Yi B, De Smet M, Snyder K, Hilliard D, Tanen M, Tanaka W, Wang AQ, Zeng W, Musson D, Winchell G, Davies MJ, Ramael S, Gottesdiener KM, Wagner JA.
• "Pharmacokinetics and pharmacodynamics of sitagliptin, an inhibitor of dipeptidyl peptidase IV, in healthy subjects: results from two randomized, double-blind,
• placebo-controlled studies with single oral doses". Clin Pharmacol Ther 78 (6): 675?8. (December 2005)