Substance
ID:449862
Names and Identifiers
IUPAC name
4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)-1,2-dihydrophthalazin-1-one hydrochloride
Synonyms
AstelinRhinolastAzelastine hydrochlorideAzeptinAzelLasticom
IUPAC Traditional name
4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)-1,2-dihydrophthalazin-1-one hydrochloride
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Used for the local treatment of allergic and vasomotor rhinitis and allergic conjunctivitis.
Salt Data
HCl
Pharmacology Properties
Mechanism of Action
Histamine H1-receptor antagonist and mediator release inhibitor
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Tasaka, K. et al., Arzneim.-Forsch., 1979, 29, 488
• Zechel, H.J. et al., Arzneim.-Forsch., 1981, 31, 1184
• Hazama, H. et al., Eur. J. Pharmacol., 1994, 259, 143