Substance
ID:449835
Names and Identifiers
IUPAC name
tetramethylpyrazine
Synonyms
ChuanxiongzineLigustrazineTetramethylpyrazine
IUPAC Traditional name
tetramethylpyrazine
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Pulmonary vasodilator
Shows antiinflammatory activity
Protect against pulmonary fibrosis
Neuroprotective
Fragrance and flavouring ingredient
Protect against renal ischemia/reperfusion injury
Bactericidal agent
Biological Source
Metab. from Bacillus subtilis; isol. from Galbanum oil.
Also in Ligusticum wallichii
Pharmacology Properties
Mechanism of Action
Apoptosis inhibitor
Free radicals scavenger
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• 3. Fan LH, Wang KZ, Cheng B, Wang CS, Dang XQ. Anti-apoptotic and neuroprotective effects of Tetramethylpyrazine following spinal cord ischemia in rabbits. BMC Neurosci. 2006 Jun 14;7:48.
• 1. Feng L, Ke N, Cheng F, Guo Y, Li S, Li Q, Li Y. The Protective Mechanism of ligustrazine Against Renal Ischemia/Reperfusion Injury. J Surg Res. 2009 May 14.
• Chinese journal of tuberculosis and respiratory diseases 1996; 19(1): 26-28.
• 2. Dai L, Hou J, and Cai HR. Using ligustrazine and Angelica sinensis treat the bleomycin-induced pulmonary fibrosis in rats.