Substance
ID:449814
Names and Identifiers
IUPAC name
2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one hydrochloride
IUPAC Traditional name
2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one hydrochloride
Synonyms
Bupropion hydrochloride
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Antidepressant
Used as a smoking cessation aid
Salt Data
HCl
Pharmacology Properties
Mechanism of Action
Dopamine reuptake inhibitor
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Ger. Pat., 1971, Wellcome, 2 059 618; CA, 76, 3551k, (synth, pharmacol)
• Dufresne, R.L. et al., Drug Intell. Clin. Pharm., 1984, 18, 957, (rev)
• Peck, A.W. et al., Br. J. Clin. Pharmacol., 1979, 7, 469, (pharmacol)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, WBJ500
• Bryant, S.G. et al., Clin. Pharm., 1983, 2, 525, (rev)
• Holm, K.J. et al., Drugs, 2000, 59, 1007-1024
• Maxwell, R.A. et al., Pharmacol. Biochem. Prop. Drug Subst., 1981, 3, 1, (rev)
• Suckow, R.F. et al., Drug Metab. Dispos., 1986, 14, 692, (metab)
• Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 280