Substance
ID:449803
Names and Identifiers
IUPAC name
benzyl N-{[(2R,4S,7R)-6,11-dimethyl-6,11-diazatetracyclo[7.6.1.02,7.012,16]hexadeca-1(16),9,12,14-tetraen-4-yl]methyl}carbamate
Synonyms
MetergolineMethergolineLiserdolAl-Migren
IUPAC Traditional name
benzyl N-{[(2R,4S,7R)-6,11-dimethyl-6,11-diazatetracyclo[7.6.1.02,7.012,16]hexadeca-1(16),9,12,14-tetraen-4-yl]methyl}carbamate
Registration numbers
CAS Number
Properties
Pharmacology Properties
Mechanism of Action
5-HT2 antagonist
Dopamine agonist
Serotonin receptor antagonist
Has moderate affinity for 5-HT6 and high affinity for 5-HT7
5-HT1 antagonist and 5-HT1D ligand
Product Information
Application(s)
Migraine disorgers therapy
Analgesic
Antipyretic
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Bagdy et al (1992) Pharmacological characterization of serotonin receptor subtypes involved in vasopressin and plasma renin activity responses to serotonin agonists. Eur.J.Pharmacol. 210 285.