Substance
ID:449725
Names and Identifiers
Synonyms
AmidoxalThiasinSulfafurazoleSoxomideGantrisinNeoxazolSulfisoxazole
IUPAC name
4-amino-N-(dimethyl-1,2-oxazol-5-yl)benzene-1-sulfonamide
IUPAC Traditional name
4-amino-N-(dimethyl-1,2-oxazol-5-yl)benzene-1-sulfonamide
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Protozoacide
Low acute toxicity
Short-acting sulfonamide used for urinary tract infections.
Antiseptic
Pharmacology Properties
Mechanism of Action
Folate antagonist
Restrict folate synthesis through competitive antagonism of PABA
Molecule Details
No Data Available
Click here to submit data
Molecular Spectra
No Data Available
Click here to submit data
References
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 207
• Chatterjee, C. et al., Acta Cryst. B, 1982, 38, 1845, (cryst struct)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 1971
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 101A, (nmr)
• Manzo, R.H. et al., J. Pharm. Sci., 1973, 62, 152, (uv)
• IARC Monog., 1980, 24, 275; Suppl. 7, 347; Suppl. 6, 502, (rev, tox)
• Kirk-Othmer Encycl. Chem. Technol., 4th edn., Wiley, 1991, 2, 876, (rev)
• Rudy, B.C. et al., Anal. Profiles Drug Subst., 1973, 2, 487, (rev, synth)
• Bult, A., Pharm. Weekbl., Sci. Ed., 1983, 5, 77, (cmr, tautom)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, SNN500
• Hoeprich, P.D., Antimicrob. Agents Chemother., 1967, 697, (pharmacol)