Substance
ID:449724
Names and Identifiers
IUPAC name
4-amino-N-(6-methoxypyridazin-3-yl)benzene-1-sulfonamide
Synonyms
SulfamethoxypyridazineSulphamethoxypyridazineKynexMidicelSulfalexLederkynExazol
IUPAC Traditional name
4-amino-N-(6-methoxypyridazin-3-yl)benzene-1-sulfonamide
Registration numbers
CAS Number
Properties
Pharmacology Properties
Mechanism of Action
Dihydrofolate reductase inhibitor
Folate antagonist
Product Information
Application(s)
Long-acting sulfonamide used for treatment of systemic infections.
Antiseptic
Low acute toxicity
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
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• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 210
• U.S. Pat., 1958, 2 833 761; CA, 52, 20216, (deriv)
• Turzcan, J. et al., J. Pharm. Sci., 1972, 61, 434, (pmr)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, AKO500
• Horie, T. et al., Chem. Pharm. Bull., 1962, 10, 580, (synth)
• Grechishkin, V.S. et al., J. Mol. Struct., 1982, 83, 345, (nqr, nmr)
• Bult, A., Pharm. Weekbl., Sci. Ed., 1983, 5, 77, (cmr)
• Basak, A.K. et al., Acta Cryst. C, 1987, 43, 735, (cryst struct)
• Kirk-Othmer Encycl. Chem. Technol., 4th edn., Wiley, 1991, 2, 876, (rev)