Substance
ID:449717
Names and Identifiers
IUPAC name
2-{2,4-dioxo-3-azatricyclo[7.3.1.05,13]trideca-1(13),5,7,9,11-pentaen-3-yl}acetic acid
Synonyms
Alrestatin
IUPAC Traditional name
2-{2,4-dioxo-3-azatricyclo[7.3.1.05,13]trideca-1(13),5,7,9,11-pentaen-3-yl}acetic acid
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Aldose reductase inhibitor investigated for treatment of diabetic polyneuropathy
Pharmacology Properties
Mechanism of Action
Aldose reductase inhibitor
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 277
• Humber, L.G., Prog. Med. Chem., 1987, 24, 299, (rev)
• Gabbay, K.H. et al., Metab., Clin. Exp., (Suppl. 1), 1979, 28, 471, (metab)
• U.S. Pat., 1974, Ayerst McKenna and Harrison, 3 821 383; CA, 81, 176158, (synth, pharmacol)
• El-Naggar, A.M. et al., Egypt. J. Chem., 1981, 24, 127, (synth)
• Varma, S.D. et al., Science (Washington, D.C.), 1975, 188, 1215, (pharmacol)