Substance
ID:449698
Names and Identifiers
IUPAC name
3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Synonyms
NifedipineNimodrelProcardiaSlofedipineNivatenAdalatAngiopineCorodayFenihidineHypolar RetardGlopirNifelatAdipineCardilateCoractenFortipineNifedicorNifedipressNifedotardNifensar XLTensipineCalanifCalcilatNifecor
IUPAC Traditional name
3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Registration numbers
CAS Number
Properties
Pharmacology Properties
Mechanism of Action
The decrease in intracellular calcium inhibits the contractile processes of smooth muscle cells,
increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.
Inhibits the influx of extracellular calcium through myocardial and vascular membrane pores by physically plugging the channel
Calcium channel blocker
causing dilation of the coronary and systemic arteries,
Product Information
Application(s)
Used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon
Coronary vasodilator
Antihypertensive agent
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
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