Substance

ID:449680

Names and Identifiers
Synonyms
TarividOflocetOxaldinOfloxacinFlobacinExocinOcufloxOflocinMefoxacin
IUPAC name
7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
IUPAC Traditional name
7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
Registration numbers
CAS Number
82419-36-1
Properties
Product Information
Application(s)
Antiseptic
Shows broad spectrum of activity against gram-positive and -negative bacteria
Antibacterial agent
Pharmacology Properties
Mechanism of Action
DNA gyrase inhibitor
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
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• Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 221; 233
• Hashimoto, K. et al., Acta Cryst. C, 1995, 51, 519
• Todd, P.A. et al., Drugs, 1991, 42, 825, (rev)
• Monk, J.P. et al., Drugs, 1987, 33, 346, (rev)
• Eur. Pat., 1982, Daiichi Seiyaku, 47 005; CA, 97, 55821b, (synth, pharmacol)
• Langtry, H.D. et al., Drugs, 1998, 56, 487-515; 895-928, (rev)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, OGI300
• Davis, R. et al., Drugs, 1994, 47, 677, (rev)
• Lamp, K.C. et al., Clin. Pharmacokinet., 1992, 22, 32, (pharmacokinet, rev)
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