Substance
ID:449677
Names and Identifiers
IUPAC name
5-amino-2-hydroxybenzoic acid
Synonyms
5-aminosalicylic acidMesalamineAsacolMesalazinePentasaFisalamineClaversalAsalitRowasaSalofalkMesalazine
IUPAC Traditional name
5-amino-2-hydroxybenzoic acid
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Low acute oral toxicity
Antiseptic
Esters used as sunscreens
Antiinflammatory agent
Drug used for treatment of ulcerative colitis
Pharmacology Properties
Mechanism of Action
Cyclooxygenase inhibitor
Prostaglandin antagonist
Molecule Details
No Data Available
Click here to submit data
Molecular Spectra
No Data Available
Click here to submit data
References
• Georgieva, M., Anal. Chim. Acta, 1978, 101, 139
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 2, 1121C, (nmr)
• CRC Atlas of Spectral Data and Physical Constants, b848, (ir, uv)
• Weil, H. et al., Ber., 1922, 55, 2664, (synth)
• Myers, B. et al., Gut, 1987, 28, 196, (metab)
• Dobson, A.J. et al., Acta Cryst. C, 1998, 54, 1632-1634, (cryst struct)
• Lepri, L. et al., J. Chromatogr., 1974, 88, 331
• Dash, A.K. et al., Anal. Profiles Drug Subst., 1998, 25, 209-242, (rev, pharmacol)
• Drain, D.J. et al., J.C.S., 1949, 1498-1503, (N-Ac)
• Hoult, J.R.S., Drugs, 1986, 32, 18, (rev)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 8427
• Prakash, A. et al., Drugs, 1999, 57, 383-408, (rev)
• Clemett, D. et al., Drugs, 2000, 59, 929-956
• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 219B, (ir)
• Shavel, J. et al., J. Am. Pharm. Assoc., 1953, 42, 402; CA, 48, 9325
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, AMM500