Substance
ID:449677
Names and Identifiers
IUPAC name
5-amino-2-hydroxybenzoic acid
Synonyms
5-aminosalicylic acidMesalamineAsacolMesalazinePentasaFisalamineClaversalAsalitRowasaSalofalkMesalazine
IUPAC Traditional name
5-amino-2-hydroxybenzoic acid
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Drug used for treatment of ulcerative colitis
Antiseptic
Esters used as sunscreens
Low acute oral toxicity
Antiinflammatory agent
Pharmacology Properties
Mechanism of Action
Cyclooxygenase inhibitor
Prostaglandin antagonist
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
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• Clemett, D. et al., Drugs, 2000, 59, 929-956
• Drain, D.J. et al., J.C.S., 1949, 1498-1503, (N-Ac)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 2, 1121C, (nmr)
• Georgieva, M., Anal. Chim. Acta, 1978, 101, 139
• Hoult, J.R.S., Drugs, 1986, 32, 18, (rev)
• Prakash, A. et al., Drugs, 1999, 57, 383-408, (rev)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 8427
• CRC Atlas of Spectral Data and Physical Constants, b848, (ir, uv)
• Weil, H. et al., Ber., 1922, 55, 2664, (synth)
• Lepri, L. et al., J. Chromatogr., 1974, 88, 331
• Myers, B. et al., Gut, 1987, 28, 196, (metab)
• Dash, A.K. et al., Anal. Profiles Drug Subst., 1998, 25, 209-242, (rev, pharmacol)
• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 219B, (ir)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, AMM500