Substance
ID:449672
Names and Identifiers
IUPAC name
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid
Synonyms
FlexinIndocinIndocidArtracinIndomedMobilanIndometacinImbrilon
IUPAC Traditional name
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid
Registration numbers
CAS Number
Properties
Pharmacology Properties
Mechanism of Action
Possible cyclooxygenase-inhibitor.
Prostaglandin-synthesis-inhibitor
Prostaglandin-antagonist
Product Information
Application(s)
Antipyretics
Antiinflammatories
Antirheumatics
Molecule Details
No Data Available
Click here to submit data
Molecular Spectra
No Data Available
Click here to submit data
References
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, IDA000
• Shen, T.Y. et al., J.A.C.S., 1963, 85, 488
• Bertazzoni, D. et al., Boll. Chim. Farm., 1970, 109, 60, (synth)
• Singh, S.P. et al., J. Het. Chem., 1978, 15, 13, (pmr)
• Yamamato, H., Chem. Pharm. Bull., 1968, 16, 17, (synth)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 19
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 5116, (synonyms)
• Oberto, G. et al., Fundam. Appl. Toxicol., 1990, 15, 800, (tox)
• O'Brien, M. et al., Anal. Profiles Drug Subst., 1984, 13, 211, (rev)
• Kaneniwa, N. et al., Chem. Pharm. Bull., 1985, 33, 3447, (synth, struct)
• Kistenmacher, T.J. et al., J.A.C.S., 1972, 94, 1340, (cryst struct)
• Shen, T.Y. et al., Adv. Drug Res., 1977, 12, 89, (rev)
• Helleberg, L., Clin. Pharmacokinet., 1981, 6, 245, (metab)