Substance
ID:449656
Names and Identifiers
IUPAC name
(6R,7R)-7-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Synonyms
CefamoxCefadroxilBidocefCefadrilCefroxilCephadroxilBaxanDuricefCefadrox
IUPAC Traditional name
(6R,7R)-7-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Broad-spectrum antibiotic effective in Gram-positive and Gram-negative bacterial infections.
It is a bactericidal antibiotic
Pharmacology Properties
Mechanism of Action
Mucopeptide-synthesis inhibitor;
Cell wall synthesis inhibitor
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Leitner, F. et al., J. Antimicrob. Chemother., Suppl. B, 1982, 10, 1, (numerous papers)
• Kemperman, G.J. et al., Eur. J. Org. Chem., 2001, 1817-1820, (synth)
• Dunn, G. et al., J. Antibiot., 1976, 29, 65, (synth)
• U.S. Pat., 1979, 4 160 863; CA, 91, 175376, (synth, cryst struct)
• Tanrisever, B. et al., Drugs, 1986, 32, 1, (rev)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 7th edn., Akademie-Verlag, 1994, 5179, (synonyms)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, DYF700
• Ger. Pat., 1973, 2 263 861; CA, 79, 78822, (synth)
• Shin, W. et al., Acta Cryst. C, 1992, 48, 1454, (cryst struct)
• Ger. Pat., 1975, 2 460 607; CA, 83, 145764, (synth)
• Neuman, M., Drugs of Today (Barcelona), 1977, 13, 471, (rev)
• Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 163