Substance
ID:449643
Names and Identifiers
Synonyms
Prednisolone hemisuccinate
IUPAC name
4-{2-[(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-14-yl]-2-oxoethoxy}-4-oxobutanoic acid
IUPAC Traditional name
4-{2-[(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-14-yl]-2-oxoethoxy}-4-oxobutanoic acid
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Immunosuppressive
Antiinflammatory,
Antiallergic agent
Pharmacology Properties
Mechanism of Action
Gluconeogenesis promoter
ACTH secretion inhibitor
Phosphorus mobilizer
Calcium mobilizer
Glucocorticoid
Glycogen deposition inhibitor
ACTH antagonist
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Gladiali, S. et al., Chem. Ind. (London), 1977, 982, (synth)
• Herzog, H.L. et al., Tetrahedron, 1962, 18, 581, (synth, ir, pmr, uv)
• Smith, L.L. et al., J.O.C., 1958, 23, 960, (spectra)
• McAleer, W.J. et al., J.O.C., 1958, 23, 508, (synth)
• Martindale, The Extra Pharmacopoeia, 28th/29th edn., Pharmaceutical Press, 1982, 12869
• Pechet, M.M. et al., J. Colloid Sci., 1959, 38, 681, (pharmacol)