Substance
ID:449635
Names and Identifiers
Synonyms
KenacortTriamcinoloneVolonAristocortFluoxiprednisoloneLederspan
IUPAC name
(1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one
IUPAC Traditional name
(1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one
Registration numbers
CAS Number
Properties
Pharmacology Properties
Mechanism of Action
ACTH secretion inhibitor
ACTH antaganist
Glycogen deposition inhibitor
Calcium mobilizer
Glucocorticoid
Gluconeogenesis promoter
Phosphorus mobilizer
Immunosuppressive
Product Information
Application(s)
Immunosuppressive
Antiinflammatory agent
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Bernstein, S. et al., J.A.C.S., 1956, 78, 5693, (synth)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 586B, (nmr)
• Fried, J. et al., J.A.C.S., 1958, 80, 2338, (synth, pharmacol)
• Florey, K., Anal. Profiles Drug Subst., 1972, 1, 367; 397; 423, (rev)
• Toft, P. et al., Can. J. Pharm. Sci., 1972, 7, 53, (ms)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, AQX250; AQY375; AQX500; AQX750
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 739
• Sieh, D.H., Anal. Profiles Drug Subst., 1982, 11, 593; 615; 651, (rev)
• Fiegel, G., Arzneim.-Forsch., 1975, 25, 560, (rev)
• Zbinovsky, V. et al., Anal. Profiles Drug Subst., 1977, 6, 579, (rev)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 6222; 7100; 7152