Substance

ID:449623

Names and Identifiers
IUPAC name
(1S,2R,10R,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one
Synonyms
Cortodoxone cortifen
IUPAC Traditional name
(1S,2R,10R,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one
Registration numbers
CAS Number
152-58-9
Properties
Pharmacology Properties
Mechanism of Action
ACTH secretion inhibitor
Phosphorus mobilizer
ACTH antagonist
Glucocorticoid
Calcium mobilizer
Gluconeogenesis promoter
Glycogen deposition inhibitor
Product Information
Application(s)
Antiinflammatory drug
Immunosuppressive
Biological Source
Found in the blood and urine of humans and other mammals
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Julian, P.L. et al. , J.A.C.S. , 1950, 72 , 5145, (synth)
• Dupont, L. et al. , Acta Cryst. , 1973, 29 , 205, (cryst struct)
• Gallagher, T.F. et al. , J.A.C.S. , 1949, 71 , 3262, (synth)
• Aldrich Library of FT-IR Spectra, 1st edn. , 1985, 2 , 1054C, (ir)
• Reichstein, T. et al. , Helv. Chim. Acta , 1938, 21 , 1197, (isol, synth)
• Tseikinskii, V.M. et al. , Bioorg. Khim. , 1979, 5 , 1537, (cryst struct)
• Aldrich Library of 13C and 1H FT NMR Spectra , 1992, 3 , 584B, (nmr)
• Smit, A. et al. , Rec. Trav. Chim. (J. R. Neth. Chem. Soc.) , 1966, 85, 731, (synth)
• Numazawa, M. et al. , J.O.C. , 1985, 50 , 81, (synth)
• Boar, R.B. , J.C.S. Perkin 1 , 1975, 1275, (pmr)
• Gonzalez, M.D. et al. , Org. Magn. Reson. , 1984, 22 , 586, (cmr)
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