Substance
ID:449622
Names and Identifiers
IUPAC name
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-diene-5,17-dione
Synonyms
Prednisone
IUPAC Traditional name
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-diene-5,17-dione
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Antiinflammatory
Immunosuppressive
Pharmacology Properties
Mechanism of Action
Glycogen deposition inhibitor
Corticosteroid
Gluconeogenesis promoter
ACTH secretion inhibitor
Phosphorus mobilizer
Calcium mobilizer
ACTH antagonist
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, PLZ000; PLZ100
• Gambertoglio, J.G. et al., J. Pharmacokinet. Biopharm., 1980, 8, 1, (rev)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 587B, (nmr)
• Herzog, H.L. et al., Tetrahedron, 1962, 18, 581, (synth)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 6213
• Ger. Pat., 1960, 1 090 208; CA, 55, 26044b, (sulfate)
• Ger. Pat., 1960, 1 089 755; CA, 55, 20008, (succinate)
• Nobile, A. et al., J.A.C.S., 1955, 77, 4184, (synth)
• Pickup, M.E., Clin. Pharmacokinet., 1979, 4, 111, (rev)
• Herzog, H.L. et al., Science (Washington, D.C.), 1955, 121, 176, (struct)
• Hickey, J.P. et al., J. Magn. Reson., 1980, 38, 501, (cmr)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 738
• Gardi, R. et al., Gazz. Chim. Ital., 1963, 93, 431, (ir, uv)