Substance
ID:449615
Names and Identifiers
IUPAC name
[2-hydroxy-3-(1H-indol-4-yloxy)propyl](propan-2-yl)amine
Synonyms
PindololViskenPrindolol
IUPAC Traditional name
[2-hydroxy-3-(1H-indol-4-yloxy)propyl](propan-2-yl)amine
Registration numbers
CAS Number
Properties
Pharmacology Properties
Mechanism of Action
Non-cardioselective beta-Adrenoceptor antagonist
Partial agonist
Sympatholytic-Beta
Possesses intrinsic sympathomimetic actions (ISA), but little membrane-stabilizing activity
5HT1A serotonin receptor antagonist
Vasodilator
Product Information
Application(s)
Used in treatment of Angina pectoris and hypertension
Vasodilator
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Frishman, W.H., N. Engl. J. Med., 1983, 308, 904, (rev, pharmacol)
• Fuji, M. et al., Chem. Pharm. Bull., 1992, 40, 2353, (synth, pmr, ms)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 637
• Tsuda, Y. et al., Chem. Pharm. Bull., 1981, 29, 3593, (synth)
• Aellig, W.H., Am. Heart J., 1982, 104, 333, (rev, pharmacol)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 3266, (synonyms)
• Kuhnert-Brandstaetter, M. et al., Sci. Pharm., 1974, 42, 234, (uv)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, VSA000
• Ishibashi, H. et al., Chem. Pharm. Bull., 1994, 42, 271, (synth)
• Rivier, J.-L. et al., Therapie, 1970, 25, 245, (pharmacol)
• Giudicelli, J.F. et al., J. Pharmacol. Exp. Ther., 1969, 168, 116, (pharmacol)
• Seemann, F. et al., Helv. Chim. Acta, 1971, 54, 2411, (synth)