Substance
ID:449607
Names and Identifiers
Synonyms
ColchicineColchisolColsaloidColchiceine methyl etherArtrichine
IUPAC name
N-[(10S)-3,4,5,14-tetramethoxy-13-oxotricyclo[9.5.0.02,7]hexadeca-1(16),2,4,6,11,14-hexaen-10-yl]acetamide
IUPAC Traditional name
N-[(10S)-3,4,5,14-tetramethoxy-13-oxotricyclo[9.5.0.02,7]hexadeca-1(16),2,4,6,11,14-hexaen-10-yl]acetamide
Registration numbers
CAS Number
Properties
Pharmacology Properties
Mechanism of Action
Reduces phagocytosis with inflammatory
Leukocyte migration inhibitor
Phagocytosis inhibitor
Interferes with kinin formation
Response abatement
Exact mechanism unknown
Product Information
Application(s)
Potential HIV inhibitor
Cytostatic
Antirheumatic
Immunosuppressive
Biological Source
Chief alkaloid from Colchicum autumnale, many other Colchicum spp., several Merendera spp., Gloriosa superba and others (Liliaceae)
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Local delivery of biodegradable microparticles containing colchicine or a colchicine analogue: effects on restenosis and implications for catheter-based drug delivery.
• J.Am.Coll.Cardiol. (26, No. 6, 1549-57, 1995)