Substance
ID:449604
Names and Identifiers
IUPAC name
(6R,7R)-3-[(acetyloxy)methyl]-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Synonyms
CephalotinCephalothinCephalosporin 871Cefalotin7-(2-Thiopheneacetamido)cephalosporanic acid
IUPAC Traditional name
(6R,7R)-3-[(acetyloxy)methyl]-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Registration numbers
CAS Number
Properties
Pharmacology Properties
Mechanism of Action
Mucopeptide synthesis inhibitor
Product Information
Application(s)
Parenteral antibiotic
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Woodward, R.B. et al., J.A.C.S., 1966, 88, 852, (synth)
• Welles, J.S., Cephalosporins Penicillins: Chem. Biol., (Flynn, E.H., Ed.), Academic Press, 1972, 583, (rev)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 138
• Simmons, R.J., Anal. Profiles Drug Subst., 1972, 1, 319, (rev)
• Ratcliffe, R. et al., Tet. Lett., 1973, 4649
• Cowley, B.R. et al., Tetrahedron, 1983, 39, 461, (synth)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 3941, (synonyms)
• Nishikawa, J. et al., J. Antibiot., 1982, 35, 1724, (ir, cmr)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, CCX250; SFQ500
• Chauvette, R.R. et al., J.A.C.S., 1962, 84, 3401, (synth)