Substance
ID:449569
Names and Identifiers
IUPAC name
(1S,2R,10R,11S,14R,15S)-15-ethyl-14-ethynyl-14-hydroxytetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one
Synonyms
Dexnorgestrel (obsol.)MirenaD -NorgestrelLevonorgestrel
IUPAC Traditional name
(1S,2R,10R,11S,14R,15S)-15-ethyl-14-ethynyl-14-hydroxytetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Tocolytic
Used in oral contraceptives
Pharmacology Properties
Mechanism of Action
Progestogen
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Horvath, G. et al., Adv. Mass Spectrom., 1978, 7B, 1280, (ms)
• Delettre, J. et al., Acta Cryst. B, 1980, 36, 1505, (cryst struct)
• Michnowicz, J. et al., Org. Mass Spectrom., 1972, 6, 765, (ms)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 1190
• U.S. Pat., 1967, 3 338 925; CA, 68, 22142, (synth)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, NNQ500; NNQ520; NNQ525
• Cleve, G. et al., Arzneim.-Forsch., 1986, 36, 784, (mol struct)
• Rufer, C. et al., Annalen, 1967, 702, 141, (synth, uv)
• Sopirak, A. et al., Anal. Profiles Drug Subst., 1975, 4, 294, (rev)
• Ranney, R.E., J. Toxicol. Environ. Health, 1977, 3, 139, (rev, metab)
• Coukell, A.J. et al., Drugs, 1998, 55, 861-887, (rev)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 6287; 6288
• DeAngelis, N.J. et al., Acta Cryst. B, 1975, 31, 2040, (struct)
• Baier, H. et al., Helv. Chim. Acta, 1985, 68, 1054, (synth, cd, abs config, uv, ir, pmr)
• Rosenberger, M. et al., Helv. Chim. Acta, 1971, 54, 2857, (synth)
• Jones, R.C. et al., Int. J. Fertil., 1979, 24, 39, (props, enantiomers)
• Smith, H. et al., J.C.S., 1964, 4472, (synth)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 591C, (nmr)
• Sauer, G. et al., Angew. Chem., Int. Ed., 1975, 14, 417, (synth)