Substance
ID:449569
Names and Identifiers
IUPAC name
(1S,2R,10R,11S,14R,15S)-15-ethyl-14-ethynyl-14-hydroxytetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one
Synonyms
Dexnorgestrel (obsol.)MirenaD -NorgestrelLevonorgestrel
IUPAC Traditional name
(1S,2R,10R,11S,14R,15S)-15-ethyl-14-ethynyl-14-hydroxytetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Tocolytic
Used in oral contraceptives
Pharmacology Properties
Mechanism of Action
Progestogen
Molecule Details
No Data Available
Click here to submit data
Molecular Spectra
No Data Available
Click here to submit data
References
• Delettre, J. et al., Acta Cryst. B, 1980, 36, 1505, (cryst struct)
• Cleve, G. et al., Arzneim.-Forsch., 1986, 36, 784, (mol struct)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 591C, (nmr)
• Rufer, C. et al., Annalen, 1967, 702, 141, (synth, uv)
• DeAngelis, N.J. et al., Acta Cryst. B, 1975, 31, 2040, (struct)
• Sopirak, A. et al., Anal. Profiles Drug Subst., 1975, 4, 294, (rev)
• Horvath, G. et al., Adv. Mass Spectrom., 1978, 7B, 1280, (ms)
• Baier, H. et al., Helv. Chim. Acta, 1985, 68, 1054, (synth, cd, abs config, uv, ir, pmr)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 6287; 6288
• Jones, R.C. et al., Int. J. Fertil., 1979, 24, 39, (props, enantiomers)
• Coukell, A.J. et al., Drugs, 1998, 55, 861-887, (rev)
• Michnowicz, J. et al., Org. Mass Spectrom., 1972, 6, 765, (ms)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 1190
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, NNQ500; NNQ520; NNQ525
• Rosenberger, M. et al., Helv. Chim. Acta, 1971, 54, 2857, (synth)
• Ranney, R.E., J. Toxicol. Environ. Health, 1977, 3, 139, (rev, metab)
• Smith, H. et al., J.C.S., 1964, 4472, (synth)
• Sauer, G. et al., Angew. Chem., Int. Ed., 1975, 14, 417, (synth)
• U.S. Pat., 1967, 3 338 925; CA, 68, 22142, (synth)