Substance
ID:449529
Names and Identifiers
IUPAC name
1-[2-(ethanesulfonyl)ethyl]-2-methyl-5-nitro-1H-imidazole
Synonyms
TricolamGlongynBioshikSimplotanFasigyneTinidazole
IUPAC Traditional name
1-[2-(ethanesulfonyl)ethyl]-2-methyl-5-nitro-1H-imidazole
Registration numbers
CAS Number
Properties
Pharmacology Properties
Mechanism of Action
The free nitro radical generated as a result of this reduction may be responsible for the antiprotozoal activity
The nitro group of tinidazole is reduced by cell extracts of Trichomonas.
Product Information
Application(s)
Antitrichomonal, antimicrobial agent
Protozoacide
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Caplar, V. et al., J. Het. Chem., 1974, 11, 1055, (synth, bibl)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 528
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 987
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, TGD250
• Carmine, A.A. et al., Drugs, 1982, 24, 85, (rev, pharmacol)
• Chasseaud, L.F. et al., Chem. Comm., 1984, 491, (cryst struct, props)
• Rao, A.K.S.B. et al., J.C.S. Perkin 1, 1989, 1352
• Nord, C.E. et al., J. Antimicrob. Chemother., (Eds.), Suppl. 8, 1982, 10, 1, (numerous papers)
• Nagarajan, K. et al., Indian J. Chem., Sect. B, 1982, 21, 1006, (pmr, uv, ms)
• Reddy, K.C. et al., Indian J. Pharm. Sci., 1982, 44, 6, (synth)