Substance

ID:449522

Names and Identifiers
IUPAC name
1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Synonyms
TequinGatifloxacin
IUPAC Traditional name
1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Registration numbers
CAS Number
Properties
Pharmacology Properties
Mechanism of Action
Inhibits the bacterial enzymes DNA gyrase and topoisomerase IV
Product Information
Application(s)
Antibacterial
Antibiotic
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Hosaka, M. et al., Antimicrob. Agents Chemother., 1992, 36, 2108; 1996, 40, 2756, (activity, pharmacol)
• Casta~ner, J. et al., Drugs of the Future, 1993, 18, 203
• Perry, C.M. et al., Drugs, 1999, 58, 683, (rev)
• Eur. Pat., 1987, Sankyo, 241 206; CA, 110, 135095, (synth, activity)
• Wakabayashi, E. et al., Antimicrob. Agents Chemother., 1994, 38, 594, (activity)
• Dalhoff, A., Expert Opin. Invest. Drugs, 1999, 8, 123