Substance
ID:449521
Names and Identifiers
IUPAC name
1-(4-methylbenzenesulfonyl)-3-{octahydrocyclopenta[c]pyrrol-2-yl}urea
Synonyms
DiamicronGliclazideGlimicronNordialexGlyclazideUnavaDiabrezide
IUPAC Traditional name
1-(4-methylbenzenesulfonyl)-3-{octahydrocyclopenta[c]pyrrol-2-yl}urea
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Antidiabetic
Oral antihyperglycaemic agent
Pharmacology Properties
Mechanism of Action
Appears to enhance glucose stimulated insulin secretion at a submaximally stimulating blood-glucose level
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Keen, H. et al., Int. Congr. Symp. Ser. R. Soc. Med., No. 20, 1980
• Palmer, K.J. et al., Drugs, 1993, 46, 92, (rev)
• Winters, C.S. et al., J. Pharm. Sci., 1994, 83, 300, (cmr, cryst struct)
• U.K. Pat., 1968, 1 153 982; CA, 70, 47290e, (synth)
• Holmes, B. et al., Drugs, 1984, 27, 301, (rev)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 279
• Duhault, J. et al., Arzneim.-Forsch., 1972, 22, 1682, (pharmacol, tox)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 7th edn., Akademie-Verlag, 1994, 4770, (synonyms)
• Parvez, M. et al., Acta Cryst. C, 1999, 55, 74-75, (cryst struct)
• Oida, T. et al., Xenobiotica, 1985, 15, 87, (metab)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, DBL700