Substance
ID:449450
Names and Identifiers
IUPAC name
4-amino-N-(3-methoxypyrazin-2-yl)benzene-1-sulfonamide
Synonyms
PolycidalSulfamethoxypyrazineDalysepLongumKelfizineSulfalene
IUPAC Traditional name
4-amino-N-(3-methoxypyrazin-2-yl)benzene-1-sulfonamide
Registration numbers
CAS Number
Properties
Pharmacology Properties
Mechanism of Action
The inhibited reaction is necessary in these organisms for the synthesis of folic acid
Competitive inhibitor of bacterial para-aminobenzoic acid (PABA), a substrate of the enzyme dihydropteroate synthetase
Product Information
Application(s)
Antiseptic
Long-acting sulfonamide used in treatment of respiratory and urinary-tract infections
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Launchbury, A.P., Pharm. J., 1975, 214, 14, (pharmacol)
• Padeiskaya, E.N. et al., Khim.-Farm. Zh., 1977, 11, 141, (rev, pharmacol)
• Botta, M. et al., J. Het. Chem., 1979, 16, 193, (synth)
• Kracmar, J. et al., Pharmazie, 1975, 30, 447, (uv)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, MFN500
• Anisimova, O.S. et al., Khim.-Farm. Zh., 1980, 14, 92, (ms)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 205