Substance
ID:449438
Names and Identifiers
IUPAC name
4-(aminomethyl)benzene-1-sulfonamide
Synonyms
Mafenide4-HomosulfanilamideHomosulSulfamylonSulfabenzamine
IUPAC Traditional name
4-(aminomethyl)benzene-1-sulfonamide
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Antiseptic
Used as an antibacterial agent in treatment of second- and third-degree burns
Pharmacology Properties
Mechanism of Action
Folic acid biosynthesis antagonist
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Japan. Pat., 1949, 177 844; CA, 45, 9404, (manuf)
• Momose, T. et al., Yakugaku Zasshi, 1950, 70, 14, (cryst struct)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 179
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, MAC000
• Bergeim, F.H. et al., J.A.C.S., 1944, 66, 1459, (synth)
• Tanaka, Y. et al., Chem. Pharm. Bull., 1965, 13, 399, (ir)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 727, (synonyms)
• Chang, Y.-T. et al., CA, 1953, 47, 7103, (tox)
• Miller, E. et al., J.A.C.S., 1940, 62, 2099, (synth)
• Chatterjee, C. et al., Acta Cryst. B, 1981, 3, 1835, (cryst struct)
• Maschka, A. et al., Monatsh. Chem., 1954, 85, 168, (uv)
• Meyer-Dulheuer, K.H. et al., Pharm. Ztg., 1965, 110
• Rakoczy, R. et al., J. Med. Chem., 1967, 10, 273, (salts)