Substance
ID:449416
Names and Identifiers
IUPAC name
5-ethyl-1-methyl-5-phenyl-1,3-diazinane-2,4,6-trione
Synonyms
MephobarbitalMebaralProminalPhemitoneMentabalMethylphenobarbitalMethylphenobarbitoneEnfenemalEnphenemalMefobarbital
IUPAC Traditional name
5-ethyl-1-methyl-5-phenyl-1,3-diazinane-2,4,6-trione
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Antispasmodic
Sedative
Analgesic
Anticonvulsant
Pharmacology Properties
Mechanism of Action
Binds brain tissue protein
Produces all levels of CNS mood alteration
Binds plasma-protein
Dose-dependent respiratory depressant
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• U.K. Pat., 1929, 339 937; CA, 25, 2738, (synth)
• Craig, C.R. et al., J. Pharmacol. Exp. Ther., 1971, 176, 35, (pharmacol)
• Advovich, H.W. et al., Can. J. Pharm. Sci., 1969, 4, 51, (pmr)
• Saferstein, R. et al., J. Assoc. Off. Anal. Chem., 1973, 56, 1234, (ms)
• Dilli, S. et al., Aust. J. Chem., 1975, 28, 2265, (synth)
• Knabe, J. et al., Arch. Pharm. (Weinheim, Ger.), 1972, 305, 54, (synth)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 2742, (synonyms)
• Murata, M. et al., Chem. Pharm. Bull., 1992, 40, 2605, (synth, R-form)
• Asada, S. et al., Bull. Chem. Soc. Jpn., 1978, 51, 3379, (cmr)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, ENB500
• Siek, T.J. et al., J. Forensic Sci., 1975, 20, 18, (uv)
• Hooper, W.D. et al., Ther. Drug Monit., 1981, 3, 39, (metab)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 301