Substance
ID:449414
Names and Identifiers
Synonyms
FurazolidoneNeftinFuroxoneNifulidone
IUPAC name
3-[(E)-[(5-nitrofuran-2-yl)methylidene]amino]-1,3-oxazolidin-2-one
IUPAC Traditional name
3-[(E)-[(5-nitrofuran-2-yl)methylidene]amino]-1,3-oxazolidin-2-one
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Antiseptic, antiprotozoal and antibacterial agent
Activity against: Escherichia coli; Staphylococcus; Proteus; Giardia lamblia.; Enterobacter aerogenes
.
Pharmacology Properties
Mechanism of Action
Interferes with several bacterial Enzyme systems
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, NGG500
• Vroomen, L.H.M. et al., Drug Metab. Rev., 1990, 22, 663
• Gever, G. et al., J.A.C.S., 1955, 77, 2277; 2282, (synth)
• Rogers, G.S. et al., Antibiot. Chemother. (Washington, D.C.), 1956, 6, 231, (pharmacol)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 837, (synonyms)
• Cohen, S.M., Carcinog. - Compr. Surv., (ed. Bryan, G.T.), Raven Press, N.Y., 1978, 171-231, (tox)
• Yurchenco, J.A. et al., Antibiot. Chemother. (Washington, D.C.), 1953, 3, 1035, (pharmacol)
• Chamberlain, R.E., J. Antimicrob. Chemother., 1976, 2, 325, (rev)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 40B, (nmr)
• IARC Monog., 1983, 31, 141; Suppl. 7, 63, (rev, tox)
• Ali, B.H., Vet. Res. Commun., 1983, 6, 1, (rev, pharmacol)
• Ali, B.H., Gen. Pharmacol., 1989, 20, 557, (rev)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 514
• Tatsumi, K. et al., Chem. Pharm. Bull., 1982, 30, 3435, (metab, tox)