Substance
ID:449376
Names and Identifiers
IUPAC name
(2S)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
Synonyms
SerotonylTripteneOxitriptanLevothym
IUPAC Traditional name
(2S)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Antidepressant
Psychostimulant
Biological Source
Metab. of Chromobacterium violaceum, constit. of the seeds of Griffonia simplicifolia.
Occurs in large amts. in Panaeolus sphinctrinus and other Panaeolus spp.
Pharmacology Properties
Mechanism of Action
Precusor of 5-hydroxytryptamine
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Iriuchijima, S. et al., Agric. Biol. Chem., 1978, 42, 843, (synth, deriv)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, HOA575; HOA600; HON800; HOO000; HOO100
• Morris, A.J. et al., J.O.C., 1957, 22, 306, (resoln, abs config)
• Van Praag, H.M., Neuropharmacology, 1983, 22, 433, (rev)
• Irie, K. et al., Chem. Pharm. Bull., 1984, 32, 2126, (synth)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 146B, (nmr)
• Witkop, B. et al., J.A.C.S., 1954, 76, 5579, (synth)
• Biochem. Prep., 1962, 9, 92, (synth)
• Tyler, V.E. et al., J. Pharm. Sci., 1964, 53, 462, (isol)
• Wakahara, A. et al., Bull. Chem. Soc. Jpn., 1973, 46, 2475, (cryst struct)
• Francis, P. et al., Biomed. Mass Spectrom., 1980, 7, 294, (ms, deriv)
• Frahn, J.L. et al., Aust. J. Chem., 1974, 27, 1367, (synth, deriv)
• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 673C; 673D, (ir)
• Bell, E.A. et al., Nature (London), 1966, 210, 529, (isol)