Substance
ID:449375
Names and Identifiers
IUPAC name
(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[4-(hydroxymethyl)phenoxy]oxane-3,4,5-triol
IUPAC Traditional name
(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[4-(hydroxymethyl)phenoxy]oxane-3,4,5-triol
Synonyms
4-O-beta-D-Glucopyranoside4-(Hydroxymethyl)phenyl beta- D -glucopyranoside4-beta- D Glucopyranosyloxybenzyl alcoholGastrodin4-Hydroxybenzyl alcohol
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Hypnotic and Sedative props.
Antihypertensive
Anticonvulsant
Biological Source
Isol. from Gastrodia elata and Galeolae septentrionalis
Pharmacology Properties
Mechanism of Action
Prevents glutamate- and NMDA-induced neurotoxicity
Increases extracellular glutamate level
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Spth, E., Monatsh. Chem., 1914, 35, 319, (synth)
• Carothers, W.H. et al., J.A.C.S., 1924, 46, 1675, (synth)
• Shannon, J.S., Aust. J. Chem., 1962, 15, 265, (ms)
• Taguchi, H. et al., Chem. Pharm. Bull., 1981, 29, 55, (Gastrodin)
• Nakatani, N. et al., Agric. Biol. Chem., 1987, 51, 2727, (synth, Gastrodin)
• Lewis, R.J., Food Additives Handbook, Van Nostrand Reinhold International, New York, 1989, MED500
• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 1, 1135B; 1135C; 1136A, (ir)
• Inoue, S. et al., Yakugaku Zasshi, 1984, 104, 42, (Gastrodin)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 2, 352B; 352C; 353B, (nmr)
• Mumford, F.E. et al., Phytochemistry, 1963, 2, 215, (isol)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, MED500
• Watanabe, H. et al., CA, 1961, 55, 16697, (isol, deriv)
• Hardegger, E. et al., Helv. Chim. Acta, 1963, 46, 1171, (isol)
• Torii, S. et al., J.O.C., 1979, 44, 3305, (synth)
• Encyclopedia of Food and Color Additives, (ed. Burdock, G.A.), CRC Press, 1997, 179-184, (derivs, occur, use)
• Aldrich Library of FT-IR Spectra: Vapor Phase, 1989, 3, 1059C; 1059D, (ir)
• Ofner, A., Helv. Chim. Acta, 1935, 18, 951, (synth)