Substance
ID:449374
Names and Identifiers
IUPAC name
5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}-4H-chromen-4-one
Synonyms
4'-Me ether, 3-O-alpha- L -rhamnopyranoside7-O-beta-D-glucopyranosideIcariin
IUPAC Traditional name
5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}-4H-chromen-4-one
Registration numbers
CAS Number
Properties
Product Information
Application(s)
Antineoplastic agent
Immunostimulant
Biological Source
Isol. from Epimedium spp.
Pharmacology Properties
Mechanism of Action
Calcium regulator
Neuronal injury inhibitor
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Jiyun, L. et al., Drugs of the Future, 1998, 23, 142-145, (Icariin, rev, pharmacol)
• Jain, A.C. et al., Aust. J. Chem., 1975, 28, 607, (synth)
• He, W. et al., Arzneim.-Forsch., 1995, 45, 910-913, (Icariin, pharmacol)
• Anam, E.A., Indian J. Heterocycl. Chem., 1997, 7, 59-62
• Miyaichi, Y. et al., Yakugaku Zasshi, 1994, 114, 186